Clark School Home UMD

ISR News Story

Kanold group research published in PNAS

ISR-affiliated Assistant Professor Patrick Kanold (Biology) and his colleagues have just had their mammalian-brain research, “Electrical synapses formed by connexin36 regulate inhibition- and experience-dependent plasticity” published in the Proceedings of the National Academy of Sciences of the United States of America (PNAS).

The research shows that elimination of electrical synapses formed by connexin36 altered inhibitory efficacy and caused frequency facilitation of inhibition consistent with a decreased GABA release in the inhibitory network. The altered inhibitory efficacy was paralleled by a failure of theta-burst long-term potentiation induction and by impaired ocular dominance plasticity in the visual cortex. Together, these data suggest a unique mechanism for regulating plasticity in the visual cortex involving synchronization of inhibitory networks via electrical synapses.

Related Articles:
Kanold study shows autism may begin early in brain development
UMD neuroscience researchers publish in the journal Neuron
Yin, Fritz, Shamma publish neuroplasticity study in Journal of Neuroscience
Kanold study in Neuron: A short stay in darkness may heal hearing woes
Researchers part of two NSF Neural & Cognitive Systems grants worth more than $1.2 million
BBI FY17 Seed Grant Winners Announced
Fritz, Shamma are collaborators on new DARPA Targeted Neuroplasticity Training Program
NSF Science Now video features 'aging brain' research of Anderson, Simon and Presacco
It’s not your ears, it’s your brain
BBI Seed Grant winners announced

August 16, 2011


Prev   Next

 

 

Current Headlines

Alumni Profile: Paul Gaske

Ephremides is PI for new ONR 'age of information' grant

UMD Hosts Third Technica with over 800 Students from Around the Country

Srivastava Named Clark School Inaugural Associate Dean for Graduate Affairs

Pamela Abshire elected IEEE Fellow

Shihab Shamma elected IEEE Fellow

Wu Named AAAS Fellow

Baras, Kenyon, Hughes Network Systems win MIPS Global Impact Award

New microsystems detect, treat bacterial biofilms that cause post-operative infections

Srivastava named Clark School Dean for Graduate Affairs

News Resources

Return to Newsroom

Search News

Archived News

Events Resources

Events Calendar