Microsystems Seminar/Nanocolloquium: Shuichi Takayama, "Biomedical Micro and Nanofluidics"
Tuesday, May 5, 2015
2460 AV Williams Building
Biomedical Micro and Nanofluidics
Micro/Nano/Molecular Biotechnology Lab
University of Michigan
A Maryland NanoCenter NANOCOLLOQUIUM
Please note the new time and location: 1:00 p.m., 2460 AV Williams Bldg.
This presentation will give an overview of efforts in our laboratory to develop microfluidic systems to control cell microenvironments and to perform high precision biochemical measurements. Microfluidic technologies to be discussed include computer-controlled microfluidics, self-switching microfluidic transistor circuitry, “reagent” microfluidics that utilize aqueous two-phase systems to enable microscale stable spatial fluidic patterning without any channels, and fracture fabrication of tunable nanochannels. Specific biomedical applications that will be discussed include microfluidic assisted reproductive technologies and in vitro fertilization including mechanics of oocyte cryopreservation, organs-on-a-chip, soft-robotics, chromatin analysis in fracture-fabricated nanochannels, and protein biomarker analysis.
Prof. Shuichi Takayama’s research interests (B.S. & M.S. from the University of Tokyo, Ph.D. from the Scripps Research Institute) started with organic synthesis. Subsequently he pursued postdoctoral studies in bioengineered microsystems at Harvard University as a Leukemia and Lymphoma Society Fellow. He is currently Professor at the University of Michigan in the Biomedical Engineering Department and Macromolecular Science and Engineering Program, and an Adjunct Professor at School of Nano-Bioscience and Chemical Engineering, Ulsan National Institute of Science and Technology (UNIST). He is an associate editor of Integrative Biology. Research topics include microfluidic models of the body such as the oviduct, lung, and cancer metastasis. He also develops aqueous two phase system micropatterning technologies, studies timing and rhythms of cell signaling, constructs self-switching fluidic circuits, and performs nanofluidic single strand chromatin analysis. Awards and honors include the NSF CAREER award, Pioneers of Miniaturization Prize from the Royal Society of Chemistry, and AIMBE Fellow.