UTRC CDS Lecture: Joao Lemos "Modelling and Control of Anesthesia"
Tuesday, April 14, 2015
1146 A V Williams
301 405 6576
United Technologies Research Center
Invited Lectures on Control and dynamical Systems
Modelling and Control of Anesthesia
Systems, Decision and Control
Instituto Superior Tecnico
Technical University of Lisbon, Portugal
| video |
Anesthesia of patients subject to general surgery comprises three components, each one induced by a specific drug in order to drive the patient to an adequate physiological state: Neuromuscular blockade (NMB), that corresponds to muscle paralysis and prevents involuntary movements, hypnosis, that places the patient in a state of self-unconsciousness, and analgesia, that relieves the patient from the stress associated to noxious stimuli (“pain”). The seminar will address the design of controllers for automatic drug administration that concern the first two components (NMB and hypnosis). Since the major issue when controlling these type of systems is major inter- and intra-patient variability, the seminar will address modelling and control issues that are able to tackle this issue. Regarding modelling, the Fokker-Planck equation will be used to relate parameter uncertainty with the time response. Regarding control, both adaptive (based on multiple models) and robust controllers will be described. The algorithms will be illustrated using actual clinical results.
J. M. Lemos is full professor of Systems, Decision and Control at IST (Instituto Superior Técnico, Technical University of Lisbon, Portugal) since 2000 and scientific responsible for the Control of Dynamic Systems Research Group at INESC-ID since its creation. After extensive periods of research work at the Faculty of Engineering of the University of Florence, Italy, under the supervision of Prof. Edoardo Mosca, he got his Ph. D. in 1989 from IST and became associate professor in 1997 and full professor in 2000. He authored or co-authored 1 book published by Springer, 45 journal papers, 16 book chapters and 165 conference (peer reviewed) papers, and supervised 10 Ph. D. thesis and cosupervised 3 other (all completed). His research interests are in the area of Computer Control including in particular, Adaptive Predictive Control, Modelling and Identification and Process Monitoring using stochastic methods. He has been or is currently involved, both either as responsible or participant, in applications to industrial processes, large scale boilers in thermoelectric plants, solar collector fields, water distribution canals, solar furnaces and biomedical systems, with emphasis on anaesthesia. He was Chairman of the Electrical Engineering Department at IST (comprising at the time over 140 professors and 40 administrative and technical staff) from October 2004 until September 2006 and Coordinator of the Post-Graduation Courses (M. Sc. And Ph. D.) in Electrical and Computer Engineering from January 2002 until September 2004. From 2007 until 2013 he has been chairman of the Scientific Board of INESC-ID. He is currently adjoint-coordinator of the M. Sc. and Ph. D. courses on Aerospace Engineering at IST.