Qualcomm Microsystems Seminar: Tony Jun Huang, "Acousto-Opto Fluidics for Lab-on-a-Chip"
Friday, December 6, 2013
1146 A.V. Williams Building
Qualcomm Microsystems Seminar Series
Lab-on-a-Chip Technologies Enabled by Acousto-Opto Fluidics
Professor, Engineering Science and Mechanics
The Pennsylvania State University
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The past decade has witnessed an explosion in lab-on-a-chip research. This rapid development has occurred mainly because of the continuous fusion of new physics into microfluidic domains. In recent years, researchers have made significant progress in joining acoustic and optical technologies with microfluidics. Optofluidics, the merger between optics and microfluidics, enables the creation of reconfigurable optical components that are otherwise difficult to implement with solid-state technology. Acoustofluidics, on the other hand, offers noninvasive solutions for many on-chip biomedical applications.
In this talk, I will present several lab-on-a-chip innovations enabled by acoustofluidics and optofluidics, including acoustic tweezers, tunable optofluidic and plasmofluidic lenses, and miniature fluorescence-activated cell sorters (FACS). These technological innovations have many advantages and are packaged in simple, elegant designs. For example, our acoustic tweezers operate at ~107 times lower power intensity than current optical tweezers. The low power intensity renders our technology noninvasive toward biological samples, as confirmed by experimental results. Moreover, the acoustic tweezers are amenable to miniaturization and versatile—they can be applied to virtually any type of cells or microparticles regardless of size, shape, or electrical/magnetic/optical properties. With the advantages in versatility, miniaturization, power consumption, and technical simplicity, our acoustic tweezers technique are expected to become a powerful tool in many applications, including tissue engineering, microarrays, stem cell biology, and drug screening/discovery.
Tony Jun Huang is a professor in the Department of Engineering Science and Mechanics at The Pennsylvania State University. He received his Ph.D. degree in Mechanical and Aerospace Engineering from the University of California, Los Angeles (UCLA) in 2005, and his B.S. and M.S. degrees in Energy and Power Engineering from Xi’an Jiaotong University, Xi’an, China, in 1996 and 1999, respectively. His research interests are acoustofluidics, optofluidics, and micro/nano systems for biomedical applications. He has authored/co-authored over 110 peer-reviewed journal publications and over 140 peer-reviewed conference papers in these fields. He serves as Vice Chair of the American Society of Mechanical Engineers (ASME) Nanoengineering Council and chair of the ASME Society-Wide Micro/Nano Technology Forum. His research findings have been recognized with awards and honors such as the 2006 Rustum and Della Roy Innovation in Materials Research Award, a 2010 National Institutes of Health (NIH) Director’s New Innovator Award, a 2011 Penn State Engineering Alumni Society Outstanding Research Award, a 2011 JALA Top Ten Breakthroughs of the Year Award, a 2012 Outstanding Young Manufacturing Engineer Award from Society for Manufacturing Engineering, a 2013 Faculty Scholar Medal from The Pennsylvania State University, and a 2013 American Asthma Foundation (AAF) Scholar Award. More information about him and his research group can be found at www.esm.psu.edu/huang/.