Auditory cortex signal processing; brain development and plasticity; sensorimotor integration; neuromechanical systems; speech recognition; neuromorphic sensors, control and VLSI; computational neuroscience; cell-based sensors

ISR is a longtime leader in advancing understanding of neural processing in the brain's auditory system, including speech processing and sound localization. Our faculty and students have made neuroscience-based advances in signal processing principles and solutions, and have developed novel neuromorphic architectures for intelligent systems. We are active in NIH BRAIN Initiative research, using neural modeling to establish causal links between neural activity and behavior. We also developed multi-pitch tracking for adverse environments, a communication technology that pulls speech out of noise and can radically improve sound quality over cell phones and in hearing aids. ISR researchers have been key in the establishment of the university’s Brain and Behavior Initiative.

Recent ISR neuroscience publications


A latent variable approach to decoding neural population activity

Matthew Whiteway, Bruno Averbeck, Daniel Butts

The authors propose a new decoding framework that exploits the low-dimensional structure of neural population variability by removing correlated variability unrelated to the decoded variable, then decoding the resulting denoised activity.


The quest for interpretable models of neural population activity

Matthew Whiteway, Daniel Butts

Research explores latent variable models for neural recording coordinated activity of large neuron populations in brain function.

Current Opinion in Neurobiology

ISR neuroscience news